Cardiogenetics MDPI

📢 Editor's Choice Articles in 2025 — Cardiogenetics
We are pleased to present our Editor’s Choice Articles in 2025.
They are highly cited articles that reflect the breadth of contemporary cardiovascular genetics, spanning from the molecular diagnosis of rare monogenic cardiac disorders to the emerging use of polygenic risk scores (PRS) in coronary artery disease (CAD).

This year's featured articles:
1️⃣ Integrating Genetic, Clinical, and Histopathological Data for Definitive Diagnosis of PRKAG2-Related Disease
https://www.mdpi.com/2035-8148/15/4/30
2️⃣ Polygenic Risk Scores and Coronary Artery Disease
https://www.mdpi.com/2035-8148/15/4/27
3️⃣ Desmosomal Versus Non-Desmosomal Arrhythmogenic Cardiomyopathies: A State-of-the-Art Review
https://www.mdpi.com/2035-8148/15/3/22
4️⃣ Cardiac Involvement in Patients with MELAS-Related mtDNA 3243A>G Variant
https://www.mdpi.com/2035-8148/15/2/16
5️⃣ The Influence of Genotype on the Cardiopulmonary Test Response in Patients Affected by Hypertrophic Cardiomyopathy
https://www.mdpi.com/2035-8148/15/2/12
6️⃣ Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?
https://www.mdpi.com/2035-8148/15/1/9
We warmly congratulate all the authors and thank our reviewers and Editorial Board for their continued support.
All articles are # OpenAccess and freely available.
📖 Explore the collection: https://bit.ly/3VpqG2u

Desmosomal Versus Non-Desmosomal Arrhythmogenic Cardiomyopathies: A State-of-the-Art Review Arrhythmogenic cardiomyopathies (ACMs) are a phenotypically and etiologically heterogeneous group of myocardial disorders characterized by fibrotic or fibro-fatty replacement of ventricular myocardium, electrical instability, and an elevated risk of sudden cardiac death. Initially identified as a ri...

📣 We are thrilled to welcome Dr. Maria Lucia Narducci, from IRCCS Foundation Agostino Gemelli University Hospital, to the Cardiogenetics Editorial Board!

To explore our full, highly distinguished Editorial Board, please visit:
https://bit.ly/4cPZz6M

📣 We are thrilled to welcome Dr. Matteo Bianco to the Cardiogenetics Editorial Board!

Dr. Matteo Bianco graduated in University of Turin in 2012. I became a cardiology fellow in University of Turin in the Specialisation School direceted by Prof. Fiorenzo Gaita. He is a resident doctor in San Luigi Gonzaga University Hospital Since 2018. He obatined a Master of Science in Intensive care cardiology in Padua University. His interests are: clinical cardiology with a particular focus in acute and chronic heart failure and cardiovascular imaging.

To explore our full, highly distinguished Editorial Board, please visit: https://bit.ly/4cPZz6M

We are thrilled to welcome Dr. Ajit Magadum to the Cardiogenetics Editorial Board!

To explore our full, highly distinguished Editorial Board, please visit: https://bit.ly/4cPZz6M

👏 We are thrilled to welcome Dr. Carmen Lopez-Sanchez from the University of Extremadura to the Cardiogenetics Editorial Board!

To explore our full, highly distinguished Editorial Board, please visit:
https://www.mdpi.com/journal/cardiogenetics/editors

👏 We are thrilled to welcome Dr. Giordano P**a to the Cardiogenetics Editorial Board!

Dr. Giordano P**a's research focuses on the alteration of platelet and endothelial cell function in vascular diseases. Several novel aspects of platelet biology are investigated in his laboratory.

Dr. P**a has taken a position as Reader in Cardiovascular Biomedicine at the Hull York Medical School, where he is a member of the Centre for Biomedicine and the Biomedical Institute for Multimorbidity.

To explore our full highly distinguished Editorial Board, please visit: https://www.mdpi.com/journal/cardiogenetics/editors

👏 We are thrilled to welcome Prof. Dr. Jacob Tfelt-Hansen to the Cardiogenetics Editorial Board!

Jacob Tfelt-Hansen is Professor and Senior Consultant at the Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen, Denmark and Department of Forensic Genetics, Faculty of Medical Sciences, University of Copenhagen, Denmark He graduated from the University of Copenhagen in 1999, defended his doctoral dissertation in 2007 and is a board certified specialist in cardiology since 2012 with a sub specialization in sudden cardiac death, inherited heart diseases and intracardiac devices. Director of inherited arrhythmia clinic, at Rigshospitalet and Deputy head of department, Department of Forensic Medicine, University of Copenhagen, Denmark. He is health representative in the EU, ERN network, for rare heart diseases Guard Heart. He is the PI on serveral major multidisciplinary projects working towards an understanding the genetic and the mechanism and the epidemiology of sudden cardiac death and primary arrhythmias.

To explore our full highly distinguished Editorial Board, please visit: https://www.mdpi.com/journal/cardiogenetics/editors

📢 New article published!

IL-6 and TNF-α in Ischemic Stroke: A Cardiogenetic Perspective on Inflammation and Clinical Outcomes

This review explores how inflammatory signaling, stroke genetics, and multi-omic approaches may shape future precision-medicine strategies — while highlighting that current evidence does not support routine cytokine genotyping or genotype-guided anti-cytokine treatment in ischemic stroke.

Read the full article: https://bit.ly/46W4dfZ

IL-6 and TNF-α in Ischemic Stroke: A Cardiogenetic Perspective on Inflammation and Clinical Outcomes Background: Ischemic stroke (IS) is a major cause of global disability, with outcomes increasingly dictated by post-ischemic neuroinflammation. Despite advances in reperfusion, many patients experience neurological decline due to divergent inflammatory responses. Objectives: This review synthesizes....

New paper published in Cardiogenetics:

Precision Medicine in Heritable Thoracic Aortic Disease (Htad): From Molecular Mechanisms to Genotype-Driven Risk Stratification and Timing of Intervention

By Than Xuan Le, Quy Phu Hoang, Dung Duc Doan, D**g Xuan Pham and Thanh Xuan Nguyen

Read more: https://bit.ly/3Ukr6qD

Vinmec Health Care System

Precision Medicine in Heritable Thoracic Aortic Disease (Htad): From Molecular Mechanisms to Genotype-Driven Risk Stratification and Timing of Intervention Background: Heritable thoracic aortic disease (HTAD) accounts for approximately 20–25% of thoracic aortic aneurysm and dissection (TAAD) cases and is a major cause of premature death in young adults. Methods: This is a narrative, non-systematic review. We performed a selective synthesis of clinica...

We're at Booth at ! 👋

Our Editor-in-Chief, Dr. Giuseppe Limongelli, stopped by earlier for a quick visit and a group photo—always great to have his support.

We're here throughout the conference, feel free to stop by for a chat!