Robert Vacha Lab

Burst or bust? What enables genome release from viral capsid? Watch this mesmerizing video.
You can learn more in https://pubs.acs.org/doi/10.1021/acsnano.1c04814

Genome release from virus capsid via large openning What enables RNA release from non-enveloped viral capsid? https://doi.org/10.1021/acsnano.1c04814

There are PhD and postdoc positions funded by ERC available in our lab. More info at https://vacha.ceitec.cz/jobs-openings/

Our member Lukáš Sukeník got his research published in ACS Nano. Congratulations!

Cargo Release from Nonenveloped Viruses and Virus-like Nanoparticles: Capsid Rupture or Pore Formation Virus-like nanoparticles are protein shells similar to wild-type viruses, and both aim to deliver their content into a cell. Unfortunately, the release mechanism of their cargo/genome remains elusive. Pores on the symmetry axes were proposed to enable the slow release of the viral genome. In contras...

Robert explained our work for Český rozhlas.

Odolnost bakterií vůči antibiotikům už nemusí být problém. Novou zbraň vyvíjí brněnští vědci Bakterie si vždycky vytvořily odolnost vůči lékům, které lékaři a biochemici proti nim objevili. Těm už v poslední době začaly docházet nápady, čím ještě by se daly bakterie potlačovat. O průlom se teď pokusí brněnští vědci, kteří zahajují výzkum peptidů. Zdá se, ž...

We have a brand new article out.

Selecting Collective Variables and Free-Energy Methods for Peptide Translocation across Membranes The selective permeability of cellular membranes is a crucial property for controlled transport into and out of cells. Molecules that can bypass the cellular machinery and spontaneously translocate across membranes could be used as therapeutics or drug carriers. Peptides are a prominent class of suc...

We can proudly announce that our group is a new ERC Consolidator Grant holder!
We will receive a €2.3 million research grant from the European Research Council for our research.
Read more here:

Robert Vacha from CEITEC Received the ERC Consolidator Grant to Fight Antibiotic Resistance on the Molecular Level Press Release Today, the European Research Council (ERC) announced the winners of its latest Consolidator Grant competition, which includes 327 top scientists and scholars from 23 countries across Europe. Funding for these researchers, as part of the…

ATTENTION! ATTENTION!

We have opened a new position for a postdoc to work on antimicrobial peptides.

Details here in the link:

http://vacha.ceitec.cz/news/hiring-postdoc/?fbclid=IwAR3vY0R3U3mXASI7iKGkx0p3TJ4Wfk_DvKrIVT1aW3-E61FqI74BtD204sI

GREAT SUCCESS!
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We were awarded ERC CZ grant to study antimicrobial peptides!
It is one of the largest direct scientific grants funded by Czech government.You can find more details in CEITEC press release.

Two Scientists from CEITEC Masaryk University Received ERC-CZ Grants. They Will Focus on Infections Two CEITEC MU projects received over 110 million CZK for research on bacterial and viral infections. Robert Vacha and Gabriel Demo both applied for the ERC CZ grant, and their research proposals were evaluated as the top two research projects from the eight supported projects in the Czech…

Dear physicists :)