Faustman Lab
Researching a cure for type 1 diabetes.
This week on "Notes from the Lab," we are joined by Zan Fleming, Founder and Executive Chairman of Kinexum, to discuss T1D Outcomes. Check out the link to the full episode below!
https://open.spotify.com/episode/7wWldWJzIoEu3xQvxFmc6f?si=mvco2Y8fQAqLW2hOmSJ8dA
Last month we shared the results of the Phase II clinical trial. We are excited to introduce you to some of the people who made the trial possible! Meet Mary, a type 1 diabetic school teacher with big plans for the Summer. Mary will talk about her HbA1c, time in range and insulin use. Like everyone treated in the trial Mary recieved a total of six BCG injections over five years and was followed for a total of eight years. Join Mary and our very own Nurse Daniela as they discuss how BCG changed her T1D experience.
Check out the full interview on our youtube channel: https://www.youtube.com/watch?v=CxNPQj2FvZA
07/08/2026
Congratulations to my MGH Neurology colleagues on publication of our BCG Alzheimer's study in Nature Communication Medicine. Prior studies have linked BCG to lower Alzheimer’s Disease (AD) or dementia as well as demonstrate favorable changes in AD related proteins. This shows that BCG can reprogram immune responses detectable in the central nervous system and demonstrate a possible biological bridge between the prior clinical observations and Alzheimer’s biology. Stay tuned. More trials coming.
Tuberculosis vaccine changes brain’s immune environment and Alzheimer’s biomarkers in older adults New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine — which is delivered through the skin to prevent tuberculosis — may remodel the human brain’s immune environment, offering a potential biological explanation for p...
This week on "Notes from the Lab" we are joined by Dr. Erika Schwarz-Cohen, who is a practicing physician but also a T1D mom. We will discuss recent updates on the BCG trials as well as her perspective as a mother of a child with type 1 diabetes.
Podcast Link: https://open.spotify.com/episode/5urYEcO1aT3Xyzi2Wwzd4C
06/18/2026
Big thank you to Live Science for their feature on the lab!
Century-old tuberculosis vaccine could help treat diabetes, trials hint. How? Repeated doses of a tuberculosis vaccine lowered insulin needs in patients with two forms of diabetes, new trial data show. But more research is needed to prove the benefit.
06/16/2026
Thank you to WBZ and CBS News for an amazing story! Check it out below!
Tuberculosis vaccine used to treat Type 1 diabetes shows promising results in clinical trial The tuberculosis vaccine is being used to treat Type 1 diabetes in clinical trials and it's showing promising results.
06/11/2026
Thank you STATNEWS for highlighting our BCG trials at the ADA
Competition for obesity drugs, clinical blind spots, and more news from ADA You're reading the web edition of STAT's ADA in 30 Seconds, from the American Diabetes Association's annual conference.
06/10/2026
Another feature in Reuters!
Older drug reprograms white blood cells, improves blood sugar in type 1 diabetes We also report on promising early data that could produce a better option for treating C. difficile-caused diarrhea, and the first vaccine for preventing Lassa fever.
06/09/2026
A wonderful feature from Nature regarding the Phase II data at the American Diabetes Association Scientific Sessions 2026!
TB vaccine from the 1920s shows promise in diabetes trial The shot reduced insulin use for people with type 1 diabetes and another autoimmune condition.
Thank you to the ADA for letting us present the results of the Phase II BCG clinical trial! The presentations are on the publications page of our web site at https://faustmanlab.org/
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