BioLife Solutions, Inc.

In a new Cell & Gene Therapy Insights interview, Editor Will Rich and Dr. Jason Acker discuss the history and evolution of biopreservation science for the cell and gene therapy field.🧬

❄️ Dr. Acker dives into how cryopreservation processes should evolve from being viewed as simply logistics to being recognized as a critical and strategic manufacturing step that directly determines the quality, cost, and clinical performance of these advanced therapies.

❄️ Rich and Dr. Acker also examine the cryobiology knowledge gap and how to bridge that in the CGT industry, and cutting-edge technologies that could change how these therapies are secured, stored, and distributed at the point of care.

Read on: https://www.insights.bio/cell-and-gene-therapy-insights/journal/article/3892/frozen-in-time-rethinking-cryopreservation-as-a-core-process-parameter-in-cell-and-gene-therapy

BioLife Solutions, Inc. has entered into a definitive merger agreement with Repligen Corporation.

Repligen hosted a conference call and webcast today to discuss the proposed transaction. The webcast will also be available for replay through Repligen’s Investor Relations website.

Read the full announcement and access the webcast details:
https://www.globenewswire.com/news-release/2026/07/22/3331162/0/en/repligen-to-acquire-biolife-solutions-expanding-its-cell-therapy-capabilities-with-market-leading-biopreservation-media.html

When we’ve discussed how to bring down the costs of cell therapy manufacturing with many of you, the conversation usually focuses on automation, facility design, and scaling up.
But what if there were downstream factors being overlooked that could significantly reduce costs? 💸

Dr. Steven Thompson suggests in Cell & Gene Therapy Review that looking earlier in the process at cytokine selection, quality, and container packaging can make a huge difference. ⚗️ 🧪

What should you consider?

💡 Cytokine type and choice affect therapeutic performance, as cytokines determine whether cells remain healthy, durable, and persistent; or if they become exhausted during manufacturing.

💡 Cell quality can matter more than cell quantity.

💡 Closed-system packaging and compatibility may reduce costs by minimizing the need for Grade A environments.

💡 Better control over cytokine inputs and handling could improve reliability and lower the cost per therapy.

Read the full scoop here:

Cell therapy’s real cost problem starts in the culture flask Some of the most actionable levers may sit earlier in the process than the industry has been looking.

Proud to support the Emily Whitehead Foundation and their Believe Bundle program.

The next ScaleReady G-Rex Grant Tour Stop is ONE WEEK away on Thursday, July 23, in Raleigh, NC. 🌳🔬

We’re changing it up this summer and sending three of our manufacturing and quality team members to this event - Hayley Steidinger, Muhamad Said, and Theron Walsh.

🗨️ They are looking forward to hearing from Batten disease advocate, Sharon King, and Dr. Bruce Thompson of Kincell Bio; also meeting attendees and learning about recent advances in solid tumor cancer through adoptive TIL therapy.

Will we see you there?

🔜 Register soon:

Raleigh G-Rex Grant Tour | ScaleReady Join the G-Rex Grant Tour in Raleigh, NC. Sign up to foster local collaboration, shape the future of cell therapy, and catalyze progress.

If you’re attending the Society for Cryobiology's CRYO2026 meeting on Wednesday and Thursday, make sure to stop by BioLife’s table. Connect with Dr. Aby J. Mathew, Dr. Alireza Abazari, Dr. Ana Clementin, and Martin Campbell in person.

Add this Session to your calendar:

🧊🔥 “Cold Science, Hot Innovations: Novel Tools and Technologies for CPA Screening and CPA Loading/Unloading” on July 15, 11:00am-1:00pm, Room 250, presented by Dr. Jason Acker.

If you can’t make it to CRYO2026, consider attending Kivi Bio’s Cryopreservation & CGT event next week, July 21-22, in Kenosha, WI.

📈 Dr. Robert Ben will be discussing how controlling ice recrystallization during cryopreservation can significantly improve cell recovery post-thaw.

Kivi Bio registration: https://www.kivibio.com/general-7/july-21-22-2026-kivi-bio-event

Did you hear that multiple networking opportunities are available at The Cell Summit ’26 meeting?

☕ Connect with speakers and other attendees during the catered coffee and lunch breaks at the Cincinnati Zoo & Botanical Garden.

⚾ Tuesday night brings us a baseball game at the Great American Ballpark in the Handlebar suite where the Cincinnati Reds and Cleveland Guardians face off.

📋 Collaborate with your case study group on Wednesday morning.

🧬 Interact with others during the Cincinnati Children's – Applied Gene & Cell Therapy Center tour on Wednesday afternoon.

If you haven’t registered for this FREE, in-person event on July 28-29, co-hosted with Cincinnati Children’s Hospital, do so soon!

➡️ Registration and details: https://biolifesolutions.com/the-cell-summit/

As regulatory bodies require more defined biologics and processes for cell and gene therapies, utilizing reproducible, consistent, and high-performance ancillary materials becomes key. 🔑

If you’re looking for better cell maintenance, expansion, and differentiation results, we now offer a family of high-purity recombinant proteins with guaranteed bioactivity. ✔️

Our latest News Post highlights our recent partnership with Qkine and why we chose specific cytokines and growth factors to better support your CGT or organoid workflow.

Available soon: Recombinant Human IL-2, IL-7, IL-15, and Growth Factor FGF-2 (145aa).

➡️ Read on for details: https://biolifesolutions.com/resource-center/insights-blog/blog-cell-therapy-grade-cytokines-growth-factors-qkine/

Will we see you at the 2026 Fred Hutch Obliteride on Saturday, August 8?

If you’re local to the Seattle, WA area, the Obliteride is a 5K run/walk/bike event that raises funds for cancer research and development at Fred Hutch Cancer Center. 🚲🚶‍➡️🏃‍♀️‍➡️

The BioLife team is excited to participate in the 5K and sponsor this event for the third year in a row!

🔸It’s not too late to sign up or volunteer. Learn more: https://www.obliteride.org/

🔸If you’d like to contribute to the BioLife team, we’d greatly appreciate your support: https://secure.fredhutch.org/site/TR?team_id=24460&pg=team&fr_id=2251